Spike proteins – Communicable Diseases Research

Omicron variant: Current insights and future directions

Article

Published on 2022-12-012022-11-15
Journal: Microbiological research
[Category] COVID19(2023년), SARS, 변종, 진단,

COVID-19 variants’ cross-reactivity on the paper microfluidic particle counting immunoassay

Article

Published on 2022-11-012022-11-15
Journal: Analytical and bioanalytical chemistry
[Category] SARS, 변종, 진단, 치료기술,

Systematic analysis and comparison of O-glycosylation of five recombinant spike proteins in β-coronaviruses

Article

Published on 2022-10-162022-11-15
Journal: Analytica chimica acta
[Category] COVID19(2023년), SARS, 변종, 치료제,

Arylcoumarin perturbs SARS-CoV-2 pathogenesis by targeting the S-protein/ACE2 interaction

Article

Published on 2022-10-112022-11-16
Journal: Scientific Reports
[Category] COVID19(2023년), SARS, 변종,

A fast, ultrasensitive SERS immunoassay to detect SARS-CoV-2 in saliva

Article

Published on 2022-10-092022-11-15
Journal: Analytica chimica acta
[Category] COVID19(2023년), SARS, 변종, 진단, 치료기술,

Neutralising activity and antibody titre in 10 patients with breakthrough infections of the SARS-CoV-2 Omicron variant in Japan

일본 SARS-CoV-2 오미크론 변이형 돌발성 감염 환자 10명의 중화 활성 및 항체 역가

Article

Published on 2022-09-012022-09-11
Journal: Journal of infection and chemotherapy : official j
[Category] COVID19(2023년), MERS, SARS, 변종, 진단,

Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination Boosts Neutralizing Activity Against Seasonal Human Coronaviruses

중증 급성 호흡기 증후군 코로나바이러스 2 백신 접종은 계절성 인간 코로나바이러스에 대한 중화 활성을 향상시킵니다

Article

Published on 2022-08-242022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat
[Category] SARS, 치료법,

[키워드] 229E activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Against analyzed average BNT162b2 causative agent ChAdOx1 ChAdOx1 nCoV-19 circulating colds common cold Concentration coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccination COVID-19 vaccinations cross-neutralization cross-protection determined by Efficiency Endemic Gene Expression HCoV HCoV-229E HCoV-NL63 HCoV-OC43 HCoVs Heterologous Huh-7 cells Human human coronavirus incubated individual inhibitory activity MERS MERS-CoV Middle East Middle East respiratory syndrome MOST neutralization neutralize Neutralizing activity NL63 nucleocapsid expression OC43 Preexisting immunity pseudoparticle pseudovirion pseudovirions reporter reporter gene respiratory SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 vaccination seasonal seasonal coronavirus seasonal coronaviruses seasonal coronaviruses. sera severe acute respiratory syndrome Coronavirus significantly increased Spike proteins these viruses vaccination Viral RNA virus
[DOI] 10.1093/cid/ciac057 PMC 바로가기 [Article Type] Article

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-Specific T Cells and Antibodies in Coronavirus Disease 2019 (COVID-19) Protection: A Prospective Study

중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 특이적 T 세포 및 항체, 코로나바이러스 질병 2019(COVID-19) 보호: 전향적 연구

Article

Published on 2022-08-242022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat
[Category] SARS, 진단, 치료법,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus analyzed antibody Antibody Response Antibody responses CD4+ CD8+ T cell CD8+ T cells clinical comparable coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 correlated COVID-19 demonstrated ELISPOT enzyme enzyme-linked immunosorbent evaluated flow cytometry followed by fraction Fractions frequencies Frequency healthcare highest IFN-γ IgG immune immune response Immunoglobulin Immunoglobulin G immunoglobulin M individual Infection interferon gamma interleukin interleukin 2 Kaplan-Meier estimator membrane nucleocapsid pandemic positive Probability Prospective PROTECT protective effect question Registration respiratory response SARS-CoV-2 SARS-COV-2 infection Spike protein Spike proteins staining T cell T cells T-cell T-cell and antibody responses T-cell Response T-cell responses the SARS-CoV-2 virus virus-specific antibodies Virus-specific IgG were infected with infection
[DOI] 10.1093/cid/ciac278 PMC 바로가기 [Article Type] Article

The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2

SARS-CoV와 SARS-CoV-2 사이의 다양한 보존된 에피토프를 표적으로 하는 항체의 중화 폭

Article

Published on 2022-08-232022-09-11
Journal: Proceedings of the National Academy of Sciences of
[Category] SARS, 변종, 진단, 치료기술, 치료제,

[키워드] antibody Antibody therapeutics Beta Beta variant breadth broad neutralizing antibody Candidates class complex conserved conversed epitopes COVID-19 cross-neutralizing antibody cryo Cryo-electron microscopy defined Delta effective electron microscopy epitope Epitopes evade exhibited hamsters immunization Infection Microscopy NAb NAbs neutralization Neutralizing Neutralizing antibodies neutralizing antibody offer omicron Omicron variant Omicron variants pseudoviruses Receptor-binding domain SARS-CoV SARS-CoV-2 SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody Spike proteins Structure structure. the receptor-binding domain the spike protein Treatment treatment of COVID-19 Vaccine variant variants variants of concern variants of SARS-CoV-2 Viral
[DOI] 10.1073/pnas.2204256119 PMC 바로가기 [Article Type] Article

Omicron Binding Mode: Contact Analysis and Dynamics of the Omicron Receptor-Binding Domain in Complex with ACE2

오미크론 결합 모드: ACE2와 복합된 오미크론 수용체 결합 도메인의 접촉 분석 및 역학

Article

Published on 2022-08-222022-09-11
Journal: Journal of Chemical Information and Modeling
[Category] COVID19(2023년), SARS, 변종,

[키워드] ACE2 affected angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antibodies B.1.1.529 binding complex complexes Complexes Contact COVID-19 Department distribution domain Dynamics edge Effect electrostatic form H-bond host receptor human ACE2 IMPROVE Interaction Lineage molecular molecular dynamics Mutation mutations N501Y omicron Omicron variant Open Science Framework Protein Proteins Receptor-binding domain resistance S-RBD Salt Bridge salt bridges SARS-CoV-2 virus spike Spike protein Spike proteins Stanford the receptor-binding domain the SARS-CoV-2 virus the Spike the WHO unique variant VoC
[DOI] 10.1021/acs.jcim.2c00397 PMC 바로가기 [Article Type] Article